Greenwich Village, 1959. Claire Bishop sits for a portrait—a gift from her husband—only to discover that what the artist has actually depicted is Claire’s suicide. Haunted by the painting, Claire is forced to redefine herself within a failing marriage and a family history of madness. Shifting ahead to 2004, we meet West, a young man with schizophrenia obsessed with a painting he encounters in a gallery: a mysterious image of a woman’s suicide. Convinced it was painted by his ex-girlfriend, West constructs an elaborate delusion involving time-travel, Hasidism, art-theft, and the terrifying power of representation. When the two characters finally meet, in the present, delusions are shattered and lives are forever changed.